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Dendritic Cells and Their Multiple Roles during Malaria Infection
Joint Authors
Boscardin, Silvia Beatriz
Amorim, Kelly N. S.
Chagas, Daniele C. G.
Sulczewski, Fernando B.
Source
Journal of Immunology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells.
This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial components as well as inflammation and on a very efficient machinery for antigen presentation.
In this way, DCs sense the presence of a myriad of pathogens, including Plasmodium spp., the causative agent of malaria.
Despite many efforts to control this infection, malaria is still responsible for high rates of morbidity and mortality.
Different groups have shown that DCs act during Plasmodium infection, and data suggest that the phenotypically distinct DCs subsets are key factors in the regulation of immunity during infection.
In this review, we will discuss the importance of DCs for the induction of immunity against the different stages of Plasmodium, the outcomes of DCs activation, and also what is currently known about Plasmodium components that trigger such activation.
American Psychological Association (APA)
Amorim, Kelly N. S.& Chagas, Daniele C. G.& Sulczewski, Fernando B.& Boscardin, Silvia Beatriz. 2016. Dendritic Cells and Their Multiple Roles during Malaria Infection. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108750
Modern Language Association (MLA)
Amorim, Kelly N. S.…[et al.]. Dendritic Cells and Their Multiple Roles during Malaria Infection. Journal of Immunology Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108750
American Medical Association (AMA)
Amorim, Kelly N. S.& Chagas, Daniele C. G.& Sulczewski, Fernando B.& Boscardin, Silvia Beatriz. Dendritic Cells and Their Multiple Roles during Malaria Infection. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108750