Expression of Pentraxin 3 and Thrombospondin 1 in Gingival Crevicular Fluid during Wound Healing after Gingivectomy in Postorthodontic Patients
Joint Authors
Surlin, Petra
Rauten, Anne Marie
Foia, Lili
Silosi, Isabela
Bogdan, Maria
Camen, Adrian
Toma, Vasilica
Cioloca, Daniel
Surlin, Valeriu
Stratul, Stefan-Ioan
Source
Journal of Immunology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Wound healing is a tissue repair process after an injury, and two of its main components are inflammation and angiogenesis, in which course a cascade of mediators is involved.
The aim of this research was to evaluate the involvement of Pentraxin 3 and Thrombospondin 1 in wound healing after periodontal surgery (gingivectomy) for gingival overgrowth during orthodontic treatment with or without magnification devices, by assessing their levels in GCF.
Methods.
From 19 patients with gingival overgrowth as a result of fixed orthodontic treatment, the overgrown gingiva was removed by gingivectomy, from one half of the mandibular arch without magnification and from the other under magnification.
Pentraxin 3 and Thrombospondin 1 were determined from gingival crevicular fluid by ELISA tests.
Results.
Statistically significant differences ( p < 0.05 ) and correlations between levels of the two biomarkers were analyzed.
Statistically significant differences were established between levels of the two biomarkers at different time points, with significant positive correlation at the point of 24 hours.
Conclusions.
Within the limitations of this study, the results seem to sustain the involvement of Pentraxin 3 and Thrombospondin 1 in the processes of inflammation and angiogenesis in wound healing of patients with postorthodontic gingivectomy.
The dynamics of Pentraxin 3 and Thrombospondin 1 levels could suggest a reduced inflammation and a faster angiogenesis using microsurgery.
American Psychological Association (APA)
Rauten, Anne Marie& Silosi, Isabela& Stratul, Stefan-Ioan& Foia, Lili& Camen, Adrian& Toma, Vasilica…[et al.]. 2016. Expression of Pentraxin 3 and Thrombospondin 1 in Gingival Crevicular Fluid during Wound Healing after Gingivectomy in Postorthodontic Patients. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108776
Modern Language Association (MLA)
Rauten, Anne Marie…[et al.]. Expression of Pentraxin 3 and Thrombospondin 1 in Gingival Crevicular Fluid during Wound Healing after Gingivectomy in Postorthodontic Patients. Journal of Immunology Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108776
American Medical Association (AMA)
Rauten, Anne Marie& Silosi, Isabela& Stratul, Stefan-Ioan& Foia, Lili& Camen, Adrian& Toma, Vasilica…[et al.]. Expression of Pentraxin 3 and Thrombospondin 1 in Gingival Crevicular Fluid during Wound Healing after Gingivectomy in Postorthodontic Patients. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108776
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108776