Sensitivity of Dendritic Cells to Microenvironment Signals
Joint Authors
Rumjanek, Vivian Mary
Motta, Juliana Maria
Source
Journal of Immunology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Dendritic cells are antigen-presenting cells capable of either activating the immune response or inducing and maintaining immune tolerance.
They do this by integrating stimuli from the environment and changing their functional status as a result of plasticity.
The modifications suffered by these cells have consequences in the way the organism may respond.
In the present work two opposing situations known to affect dendritic cells are analyzed: tumor growth, leading to a microenvironment that favors the induction of a tolerogenic profile, and organ transplantation, which leads to a proinflammatory profile.
Lessons learned from these situations may help to understand the mechanisms of modulation resulting not only from the above circumstances, but also from other pathologies.
American Psychological Association (APA)
Motta, Juliana Maria& Rumjanek, Vivian Mary. 2016. Sensitivity of Dendritic Cells to Microenvironment Signals. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108796
Modern Language Association (MLA)
Motta, Juliana Maria& Rumjanek, Vivian Mary. Sensitivity of Dendritic Cells to Microenvironment Signals. Journal of Immunology Research No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1108796
American Medical Association (AMA)
Motta, Juliana Maria& Rumjanek, Vivian Mary. Sensitivity of Dendritic Cells to Microenvironment Signals. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108796
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108796