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The Toll of Vascular Insufficiency: Implications for the Management of Peripheral Arterial Disease
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Peripheral artery disease (PAD) can result in limb loss within six months of diagnosis in a subset of patients who cannot undergo endovascular or surgical revascularization yet continues to maintain a marginal position in cardiovascular research.
While a body of literature continues to grow describing the role of danger signaling and innate immunity in cardiac biology, the role of these pathways in the ischemic myopathy associated with PAD has not been extensively studied.
The following report will review the current literature on the role of Toll-like receptor (TLR) signaling in cardiovascular biology as well as in nonischemic myopathy.
While attenuation of TLR signaling has not been shown to be clinically useful in the treatment of infectious inflammation, it may show promise in the management of severe arterial insufficiency.
American Psychological Association (APA)
Xu, Jun& Sachdev, Ulka. 2016. The Toll of Vascular Insufficiency: Implications for the Management of Peripheral Arterial Disease. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108890
Modern Language Association (MLA)
Xu, Jun& Sachdev, Ulka. The Toll of Vascular Insufficiency: Implications for the Management of Peripheral Arterial Disease. Journal of Immunology Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1108890
American Medical Association (AMA)
Xu, Jun& Sachdev, Ulka. The Toll of Vascular Insufficiency: Implications for the Management of Peripheral Arterial Disease. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108890
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108890