An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment

Abstract EN

Inflamm-aging is a challenging and promising new branch of aging-related research fields that includes areas such as immunosenescence.

Increasing evidence indicates that inflamm-aging is intensively associated with many aging diseases, such as Alzheimer’s disease, atherosclerosis, heart disease, type II diabetes, and cancer.

Mounting studies have focused on the role of inflamm-aging in disease progression and many advances have been made in the last decade.

However, the underlying mechanisms by which inflamm-aging affects pathological changes and disease development are still unclear.

Here, we review studies of inflamm-aging that explore the concept, pathological features, mechanisms, intervention, and the therapeutic strategies of inflamm-aging in disease progression.