![](/images/graphics-bg.png)
Effects of a Moderately Lower Temperature on the Proliferation and Degranulation of Rat Mast Cells
Joint Authors
Wang, Ruoyu
Yin, Xiaoqin
Zhang, Hui
Wang, Jiwei
Chen, Lin
Chen, Jingwen
Han, Xiaodong
Xiang, Zou
Li, Dongmei
Source
Journal of Immunology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Mast cells are traditionally considered as key effector cells in IgE-mediated allergic diseases.
However, the roles of mast cells have also been implicated in diverse physiological and pathological processes.
Mast cells are distributed in various organs and tissues of various species.
Some of the organs and tissues, such as testis, skin, and the upper part of the respiratory tract, have a temperature that is lower than the body’s core temperature.
The purpose of the present study was to investigate the effects of a lower temperature on the proliferation and degranulation of rat mast cells.
Here, we demonstrate that cell growth was retarded at 35°C compared to 37°C for both rat peritoneal mast cells (RPMC) and RBL-2H3, a rat mast cell line.
Furthermore, RPMC became more susceptible to degranulation at 35°C compared to 37°C.
In contrast, degranulation of RBL-2H3 was not as sensitive to temperature change as RPMC.
The functionality of mast cells in unique organs with a lower temperature warrants further analysis.
American Psychological Association (APA)
Wang, Ruoyu& Yin, Xiaoqin& Zhang, Hui& Wang, Jiwei& Chen, Lin& Chen, Jingwen…[et al.]. 2016. Effects of a Moderately Lower Temperature on the Proliferation and Degranulation of Rat Mast Cells. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108897
Modern Language Association (MLA)
Wang, Ruoyu…[et al.]. Effects of a Moderately Lower Temperature on the Proliferation and Degranulation of Rat Mast Cells. Journal of Immunology Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108897
American Medical Association (AMA)
Wang, Ruoyu& Yin, Xiaoqin& Zhang, Hui& Wang, Jiwei& Chen, Lin& Chen, Jingwen…[et al.]. Effects of a Moderately Lower Temperature on the Proliferation and Degranulation of Rat Mast Cells. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108897
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1108897