Effect of Multimodal Pore Channels on Cargo Release from Mesoporous Silica Nanoparticles
Joint Authors
Jadhav, Sushilkumar A.
Brunella, Valentina
Berlier, Gloria
Ugazio, Elena
Scalarone, Dominique
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Mesoporous silica nanoparticles (MSNs) with multimodal pore channels were fully characterized by TEM, nitrogen adsorption-desorption, and DLS analyses.
MSNs with average diameter of 200 nm with dual pore channel zones with pore diameters of 1.3–2.6 and 4 nm were tested for their use in drug delivery application.
Important role of the multimodal pore systems present on MSNs on the quantitative release of model drug ibuprofen was investigated.
The results obtained revealed that the release profile for ibuprofen clearly shows distinct zones which can be attributed to the respective porous channel zones present on the particles.
The fluctuations in the concentration of ibuprofen during the prolonged release from MSNs were caused by the multimodal pore channel systems.
American Psychological Association (APA)
Jadhav, Sushilkumar A.& Brunella, Valentina& Berlier, Gloria& Ugazio, Elena& Scalarone, Dominique. 2016. Effect of Multimodal Pore Channels on Cargo Release from Mesoporous Silica Nanoparticles. Journal of Nanomaterials،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109003
Modern Language Association (MLA)
Jadhav, Sushilkumar A.…[et al.]. Effect of Multimodal Pore Channels on Cargo Release from Mesoporous Silica Nanoparticles. Journal of Nanomaterials No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109003
American Medical Association (AMA)
Jadhav, Sushilkumar A.& Brunella, Valentina& Berlier, Gloria& Ugazio, Elena& Scalarone, Dominique. Effect of Multimodal Pore Channels on Cargo Release from Mesoporous Silica Nanoparticles. Journal of Nanomaterials. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109003
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109003