A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery
Joint Authors
de Gara, Christopher J.
Karmali, Shahzeer
Dang, Jerry
Chow, Alexandra
Shi, Xinzhe
Switzer, Noah J.
Gill, Richdeep S.
Birch, Daniel W.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The utility of bariatric surgery in type 1 diabetes remains controversial.
The aim of the present study is to evaluate glycemic control outcomes in obese patients with type 1 diabetes after bariatric surgery.
Methods.
A comprehensive search of electronic databases was completed.
Inclusion criteria included human adult subjects with BMI ≥35 kg/m2 and a confirmed diagnosis of type 1 diabetes who underwent a bariatric surgical procedure.
Results.
Thirteen primary studies (86 patients) were included.
Subjects had a mean age of 41.16 ± 6.76 years with a mean BMI of 42.50 ± 2.65 kg/m2.
There was a marked reduction in BMI postoperatively at 12 months and at study endpoint to 29.55 ± 1.76 kg/m2 ( P < 0.00001 ) and 30.63 ± 2.09 kg/m2 ( P < 0.00001 ), respectively.
Preoperative weighted mean total daily insulin requirement was 98 ± 26 IU/d, which decreased significantly to 36 ± 15 IU/d ( P < 0.00001 ) and 42 ± 11 IU/d ( P < 0.00001 ) at 12 months and at study endpoint, respectively.
An improvement in HbA1c was also seen from 8.46 ± 0.78 % preoperatively to 7.95 ± 0.55 % ( P = 0.01 ) and 8.13 ± 0.86 % ( P = 0.03 ) at 12 months and at study endpoint, respectively.
Conclusion.
Bariatric surgery in patients with type 1 diabetes leads to significant reductions in BMI and improvements in glycemic control.
American Psychological Association (APA)
Chow, Alexandra& Switzer, Noah J.& Dang, Jerry& Shi, Xinzhe& de Gara, Christopher J.& Birch, Daniel W.…[et al.]. 2016. A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery. Journal of Obesity،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109752
Modern Language Association (MLA)
Chow, Alexandra…[et al.]. A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery. Journal of Obesity No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109752
American Medical Association (AMA)
Chow, Alexandra& Switzer, Noah J.& Dang, Jerry& Shi, Xinzhe& de Gara, Christopher J.& Birch, Daniel W.…[et al.]. A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery. Journal of Obesity. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109752
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109752