![](/images/graphics-bg.png)
The Obesity Paradox and Heart Failure: A Systematic Review of a Decade of Evidence
Joint Authors
Oga, Emmanuel Aja
Eseyin, Olabimpe Ruth
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
There is scientific consensus that obesity increases the risk of cardiovascular diseases, including heart failure.
However, among persons who already have heart failure, outcomes seem to be better in obese persons as compared with lean persons: this has been termed the obesity paradox, the mechanisms of which remain unclear.
This study systematically reviewed the evidence of the relationship between heart failure mortality (and survival) and weight status.
Search of the PubMed/MEDLINE and EMBASE databases was done according to the PRISMA protocol.
The initial search identified 9879 potentially relevant papers, out of which ten studies met the inclusion criteria.
One study was a randomized clinical trial and 9 were observational cohort studies: 6 prospective and 3 retrospective studies.
All studies used the BMI, WC, or TSF as measure of body fatness and NYHA Classification of Heart Failure and had single outcomes, death, as study endpoint.
All studies included in review were longitudinal studies.
All ten studies reported improved outcomes for obese heart failure patients as compared with their normal weight counterparts; worse prognosis was demonstrated for extreme obesity ( B M I > 40 kg/m2).
The findings of this review will be of significance in informing the practice of asking obese persons with heart failure to lose weight.
However, any such recommendation on weight loss must be consequent upon more conclusive evidence on the mechanisms of the obesity paradox in heart failure and exclusion of collider bias.
American Psychological Association (APA)
Oga, Emmanuel Aja& Eseyin, Olabimpe Ruth. 2016. The Obesity Paradox and Heart Failure: A Systematic Review of a Decade of Evidence. Journal of Obesity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1109788
Modern Language Association (MLA)
Oga, Emmanuel Aja& Eseyin, Olabimpe Ruth. The Obesity Paradox and Heart Failure: A Systematic Review of a Decade of Evidence. Journal of Obesity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1109788
American Medical Association (AMA)
Oga, Emmanuel Aja& Eseyin, Olabimpe Ruth. The Obesity Paradox and Heart Failure: A Systematic Review of a Decade of Evidence. Journal of Obesity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1109788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109788