Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy
Joint Authors
Şahin, Muhammed
Türkcü, Fatih Mehmet
Elbey, Bilal
Yüksel, Harun
Şahin, Alparslan
Cingü, Abdullah Kürşat
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
We aimed to investigate the mean platelet volume (MPV) of the patients with nonarteritic anterior ischemic optic neuropathy (NAION).
Methods.
The medical records of 46 patients with the diagnosis of NAION and 90 control subjects were retrospectively evaluated.
All participants underwent complete ocular examination including intraocular pressure (IOP) measurement.
Hematocrit, MPV, hemoglobin, and platelet levels of the patients with NAION were compared with those of control subjects.
Results.
There was no significant difference between the groups in platelet counts (p=0.76).
NAION group had significantly higher MPV values (8.25±1.26 fL) than that of control subjects (7.64±1.01 fL) (p<0.001).
Multivariate logistic regression analysis showed that MPV is an independent predictor of NAION (odds ratio = 1.61; 95% confidence interval (CI) = 1.13–2.28; p=0.007).
The mean IOP was significantly higher in NAION group (p<0.001).
IOP was also found as an independent predictor of NAION according to the regression analysis (OR = 1.27; 95% CI = 1.08–1.48; p=0.003).
Conclusion.
Our results demonstrated that the MPV values were significantly higher in NAION patients, suggesting that larger platelets may contribute to the pathogenesis of the NAION.
American Psychological Association (APA)
Şahin, Muhammed& Şahin, Alparslan& Elbey, Bilal& Yüksel, Harun& Türkcü, Fatih Mehmet& Cingü, Abdullah Kürşat. 2016. Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1109809
Modern Language Association (MLA)
Şahin, Muhammed…[et al.]. Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy. Journal of Ophthalmology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1109809
American Medical Association (AMA)
Şahin, Muhammed& Şahin, Alparslan& Elbey, Bilal& Yüksel, Harun& Türkcü, Fatih Mehmet& Cingü, Abdullah Kürşat. Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1109809
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109809