Accelerated Corneal Collagen Cross-Linking Using Topography-Guided UV-A Energy Emission: Preliminary Clinical and Morphological Outcomes
Joint Authors
Moramarco, Antonio
Traversi, Claudio
Iovieno, Alfonso
Fontana, Luigi
Baiocchi, Stefano
Mazzotta, Cosimo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To assess the clinical and morphological outcomes of topography-guided accelerated corneal cross-linking.
Design.
Retrospective case series.
Methods.
21 eyes of 20 patients with progressive keratoconus were enrolled.
All patients underwent accelerated cross-linking using an ultraviolet-A (UVA) exposure with an energy release varying from 7.2 J/cm2 up to 15 J/cm2, according to the topographic corneal curvature.
Uncorrected (UDVA) and corrected (CDVA) distance visual acuity, topography, in vivo confocal microscopy (IVCM), and anterior segment optic coherence tomography (AS-OCT) were evaluated preoperatively and at the 1, 3, 6, and 12 months postoperatively.
Results.
12 months after surgery UDVA and CDVA did not significantly vary from preoperative values.
The average topographic astigmatism decreased from -4.61±0.74 diopters (D) to -3.20±0.81 D and coma aberration improved from 0.95 ± 0.03 μm to 0.88 ± 0.04 μm after surgery.
AS-OCT and IVCM documented differential effects on the treated areas using different energies doses.
The depths of demarcation line and keratocyte apoptosis were assessed.
Conclusions.
Preliminary results show correspondence between the energy dose applied and the microstructural stromal changes induced by the cross-linking at various depths in different areas of treated cornea.
One year after surgery a significant reduction in the topographic astigmatism and comatic aberration was detected.
None of the patients developed significant complications.
American Psychological Association (APA)
Mazzotta, Cosimo& Moramarco, Antonio& Traversi, Claudio& Baiocchi, Stefano& Iovieno, Alfonso& Fontana, Luigi. 2016. Accelerated Corneal Collagen Cross-Linking Using Topography-Guided UV-A Energy Emission: Preliminary Clinical and Morphological Outcomes. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1109879
Modern Language Association (MLA)
Mazzotta, Cosimo…[et al.]. Accelerated Corneal Collagen Cross-Linking Using Topography-Guided UV-A Energy Emission: Preliminary Clinical and Morphological Outcomes. Journal of Ophthalmology No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1109879
American Medical Association (AMA)
Mazzotta, Cosimo& Moramarco, Antonio& Traversi, Claudio& Baiocchi, Stefano& Iovieno, Alfonso& Fontana, Luigi. Accelerated Corneal Collagen Cross-Linking Using Topography-Guided UV-A Energy Emission: Preliminary Clinical and Morphological Outcomes. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1109879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109879