![](/images/graphics-bg.png)
Usefulness of Discarded Vitreous Samples from Routine Vitrectomy
Joint Authors
Dietrich, Helena Luiza Douat
Zoroquiain, Pablo
Vilà, Natàlia
Chen, John C.
Galic, I. John
Kapusta, Michael A.
Bravo-Filho, Vasco
Burnier, Miguel N.
Antecka, Emilia
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To describe the histopathological features of vitreous samples obtained after vitrectomy surgery from diabetic and nondiabetic patients.
Methods.
Vitreous specimens from 137 patients who underwent vitrectomy for different clinical conditions were analysed.
All samples were centrifuged and each resulting pellet was fixed and processed as part of routine paraffin section histopathology.
The histopathological features were categorized in a semiquantitative fashion.
The samples from diabetic and nondiabetic patients were compared.
Results.
The 125 included patients (58 diabetic, 60% males) were aged 64.2 ± 13.9 years.
The presence of hemorrhage, inflammatory cells, and histiocytes was significantly higher in the diabetic group ( P < 0.001 , P = 0.028 , and P = 0.016 , resp.), showing more vessels ( P < 0.001 ) and ghost vessels ( P = 0.049 ).
The presence of inflammatory cells was the feature with the highest sensitivity for detecting diabetes mellitus (98%) and also the highest negative predictive value (89%).
In the multivariate analysis, three variables emerged as independent significant predictors of diabetes in vitrectomy samples: hemorrhage, endothelial-lined vessels, and age ( P < 0.001 , P < 0.001 , and P = 0.019 , resp.).
Conclusions.
Different histopathological features can be found in vitreous samples from diabetic patients.
Analysis of vitrectomy samples may serve as a tool for diabetes management.
American Psychological Association (APA)
Vilà, Natàlia& Zoroquiain, Pablo& Bravo-Filho, Vasco& Antecka, Emilia& Dietrich, Helena Luiza Douat& Chen, John C.…[et al.]. 2016. Usefulness of Discarded Vitreous Samples from Routine Vitrectomy. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109887
Modern Language Association (MLA)
Vilà, Natàlia…[et al.]. Usefulness of Discarded Vitreous Samples from Routine Vitrectomy. Journal of Ophthalmology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1109887
American Medical Association (AMA)
Vilà, Natàlia& Zoroquiain, Pablo& Bravo-Filho, Vasco& Antecka, Emilia& Dietrich, Helena Luiza Douat& Chen, John C.…[et al.]. Usefulness of Discarded Vitreous Samples from Routine Vitrectomy. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109887
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109887