Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method
Joint Authors
Li, Miaoling
Zhang, Xiongze
Wen, Feng
Ji, Yuying
Zuo, Chengguo
Lin, Mingkai
Mi, Lan
Liu, Bing
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To investigate macular pigment optical density (MPOD) and its relationship with retinal thickness in primary open angle glaucoma (POAG) patients using the one-wavelength reflectometry method.
Methods.
A total of 30 eyes from 30 POAG patients (18 males and 12 females, mean age 47.27±16.93) and 52 eyes from 52 controls (27 males and 25 females, mean age 49.54±19.15) were included in this prospective, observational, case-control study.
MPOD was measured in a 7-degree area using one-wavelength reflectometry method.
Two parameters, max and mean optical density (OD), were used for analyses.
Spectral-domain-optical coherence tomography was used to measure retinal thickness, including central retinal thickness (CRT), the macular ganglion cell complex (GCC), and the circumpapillary retinal nerve fiber layer (RNFL).
Results.
Both maxOD and meanOD were significantly reduced in POAG patients compared with normal subjects (P<0.001).
GCC, CRT, and RNFL thicknesses were also significantly reduced in POAG patients (P<0.001).
GCC thickness had a positive relationship with MPOD.
Conclusions.
MPOD within the 7-degree area was significantly lower in Chinese POAG patients than in control subjects, and GCC thickness was significantly and positively associated with MPOD.
Whether the observed lower MPOD in POAG contributes to the disease process or is secondary to pathological changes caused by the disease (such as loss of ganglion cells) warrants further and longitudinal study.
American Psychological Association (APA)
Ji, Yuying& Zuo, Chengguo& Lin, Mingkai& Zhang, Xiongze& Li, Miaoling& Mi, Lan…[et al.]. 2016. Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109905
Modern Language Association (MLA)
Ji, Yuying…[et al.]. Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109905
American Medical Association (AMA)
Ji, Yuying& Zuo, Chengguo& Lin, Mingkai& Zhang, Xiongze& Li, Miaoling& Mi, Lan…[et al.]. Macular Pigment Optical Density in Chinese Primary Open Angle Glaucoma Using the One-Wavelength Reflectometry Method. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109905
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109905