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Corneal Biomechanics Determination in Healthy Myopic Subjects
Joint Authors
Qiu, Kunliang
Lu, Xuehui
Zhang, Riping
Wang, Geng
Zhang, Mingzhi
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To determine the corneal biomechanical properties by using the Ocular Response Analyzer™ and to investigate potential factors associated with the corneal biomechanics in healthy myopic subjects.
Methods.
135 eyes from 135 healthy myopic subjects were included in this cross-sectional observational study.
Cornea hysteresis (CH), corneal resistance factor (CRF), cornea-compensated intraocular pressure (IOPcc), and Goldmann-correlated intraocular pressure (IOPg) were determined with the Reichert Ocular Response Analyzer (ORA).
Univariate and multivariate regression analyses were performed to investigate factors associated with corneal biomechanics.
Results.
The mean CH and CRF were 9.82 ± 1.34 mmHg and 9.64 ± 1.57 mmHg, respectively.
In univariate regression analysis, CH was significantly correlated with axial length, refraction, central corneal thickness (CCT), and IOPg ( r = - 0.27 , 0.23, 0.45, and 0.21, resp.; all with p ≤ 0.015 ), but not with corneal curvature or age; CRF was significantly correlated with CCT and IOPg ( r = 0.52 and 0.70, resp.; all with p < 0.001 ), but not with axial length/refraction, corneal curvature, or age.
In multivariate regression analysis, axial length, IOPcc, and CCT were found to be independently associated with CH, while CCT and IOPg were associated with CRF.
Conclusions.
Both CH and CRF were positively correlated with CCT.
Lower CH but not CRF was associated with increasing degree of myopia.
Evaluation of corneal biomechanical properties should take CCT and myopic status into consideration.
American Psychological Association (APA)
Qiu, Kunliang& Lu, Xuehui& Zhang, Riping& Wang, Geng& Zhang, Mingzhi. 2016. Corneal Biomechanics Determination in Healthy Myopic Subjects. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109906
Modern Language Association (MLA)
Qiu, Kunliang…[et al.]. Corneal Biomechanics Determination in Healthy Myopic Subjects. Journal of Ophthalmology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1109906
American Medical Association (AMA)
Qiu, Kunliang& Lu, Xuehui& Zhang, Riping& Wang, Geng& Zhang, Mingzhi. Corneal Biomechanics Determination in Healthy Myopic Subjects. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109906
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109906