Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population
Joint Authors
Zhang, Rui
Qian, Jiang
Guo, Jie
Yuan, Yifei
Xue, Kang
Yue, Han
Chen, Ling
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To describe the clinical manifestations and treatment outcomes of syphilitic uveitis in a Chinese population.
Methods.
This is a retrospective case series of 15 consecutive patients with syphilitic uveitis treated at a uveitis referral center between 2012 and 2015.
Results.
Fifteen patients were diagnosed with syphilitic uveitis based on positive serological tests.
Nine patients were male.
Coinfection with human immunodeficiency virus was detected in two patients.
Twenty eyes presented with panuveitis and all patients had posterior involvement.
The most frequent manifestations were retinal vasculitis and papillitis, while syphilitic posterior placoid chorioretinitis was only found in three eyes.
All patients received systemic penicillin therapy according to CDC guidelines.
Nine patients were misdiagnosed before presenting to our center and the delay in treatment with penicillin was associated with poor final visual outcomes ( P < 0.05 ).
Conclusions.
In our series, both male and female were almost equally affected and coinfection of syphilis with human immunodeficiency virus was uncommon.
All patients in this study had posterior involvement and the most common manifestations were retinal vasculitis and papillitis.
Syphilis should be considered as an important differential diagnosis especially for posterior uveitis and panuveitis.
Early diagnosis and appropriate treatment are important for visual prognosis.
American Psychological Association (APA)
Zhang, Rui& Qian, Jiang& Guo, Jie& Yuan, Yifei& Xue, Kang& Yue, Han…[et al.]. 2016. Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1109907
Modern Language Association (MLA)
Zhang, Rui…[et al.]. Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population. Journal of Ophthalmology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1109907
American Medical Association (AMA)
Zhang, Rui& Qian, Jiang& Guo, Jie& Yuan, Yifei& Xue, Kang& Yue, Han…[et al.]. Clinical Manifestations and Treatment Outcomes of Syphilitic Uveitis in a Chinese Population. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1109907
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109907