Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study
Joint Authors
Mahmoud, Ramadan A.
El-Mazary, Abdel-Azeem M.
Anbar, Mohamed
Ahmed, Ahmed R. H.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To investigate tear function, ocular manifestations, and squamous metaplasia of the conjunctival epithelium (SMCE) in children with end stage renal failure (ESRF) on dialysis.
Methods.
Thirty children with ESRF and 20 age and sex matched controls during the period from January 2014 to May 2015 underwent full ophthalmologic examination and the tear function was investigated by the Schirmer and tear film break-up time (TBUT) tests.
SMCE was evaluated by impression cytology and immunocytochemistry.
The correlations of tear function status with ESRF-related clinical and biochemical variables were measured statistically.
Results.
Dry eye symptoms were detected in 26% of children with ESRF, compared with none of the controls ( P = 0.05 ) and SMCE was almost absent.
Values of the Schirmer and TBUT tests were significantly lower in children with ESRF for right eye ( t = 24.63 , P = 0.01 , and t = 11.9 , P = 0.002 , resp.) and left eye ( t = 24.7 , P = 0.02 , and t = 11.4 , P = 0.0004 , resp.).
TBUT and the Schirmer test values were correlated inversely with the duration of ESRF ( R = - 0.45 , P = 0.01 , and R = - 0.46 , P = 0.01 , resp.) and with the duration of dialysis ( R = - 0.39 , P = 0.03 , and R = - 0.45 , P = 0.01 , resp.).
None of the following parameters was associated with distorted tear function including serum creatinine, electrolytes, parathyroid hormone, total protein, albumin, CBC parameters, and systolic or diastolic blood pressure.
Conclusion.
The basal tear secretion and tear film stability were lower while the dry eye symptoms such as itching and redness were more common among children with ESRF.
The duration of ESRF and dialysis duration seem to be related to the disturbances in tear secretion and tear film stability.
However, SMCE is very rare.
American Psychological Association (APA)
Anbar, Mohamed& Ahmed, Ahmed R. H.& El-Mazary, Abdel-Azeem M.& Mahmoud, Ramadan A.. 2016. Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109972
Modern Language Association (MLA)
Anbar, Mohamed…[et al.]. Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109972
American Medical Association (AMA)
Anbar, Mohamed& Ahmed, Ahmed R. H.& El-Mazary, Abdel-Azeem M.& Mahmoud, Ramadan A.. Ocular Surface Disorders in a Group of Egyptian Children with End Stage Renal Failure on Dialysis: A Cross-Sectional Study. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109972