Keratorefractive Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Eyes
Joint Authors
Du, Zhiyu
Yan, Pisong
Luo, Qiang
Zhang, Dan
Zhang, Yu
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate high intensity focused ultrasound (HIFU) as an innovation and noninvasive technique to correct presbyopia by altering corneal curvature in the rabbit eye.
Methods.
Eighteen enucleated rabbit eyes were treated with a prototype HIFU keratoplasty.
According to the therapy power, these eyes were divided three groups: group 1 (1 W), group 2 (2 W), and group 3 (3 W).
The change in corneal power was quantified by a Sirius Scheimpflug camera.
Light microscopy (LM) and transmission electron microscopy (TEM) were performed to determine the effect on the corneal stroma.
Results.
In the treated eyes, the corneal curvature increases from 49.42 ± 0.30 diopters (D) and 48.00 ± 1.95 D before procedure to 51.37 ± 1.11 D and 57.00 ± 1.84 D after HIFU keratoplasty application in groups 1 and 3, respectively.
The major axis and minor axis of the focal region got longer when the powers of the HIFU got increased; the difference was statistically significant ( p < 0.05 ).
LM and TEM showed HIFU-induced shrinkage of corneal stromal collagen with little disturbance to the underlying epithelium.
Conclusions.
We have preliminarily exploited HIFU to establish a new technique for correcting presbyopia.
HIFU keratoplasty will be a good application prospect for treating presbyopia.
American Psychological Association (APA)
Du, Zhiyu& Yan, Pisong& Luo, Qiang& Zhang, Dan& Zhang, Yu. 2016. Keratorefractive Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Eyes. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109985
Modern Language Association (MLA)
Du, Zhiyu…[et al.]. Keratorefractive Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Eyes. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109985
American Medical Association (AMA)
Du, Zhiyu& Yan, Pisong& Luo, Qiang& Zhang, Dan& Zhang, Yu. Keratorefractive Effect of High Intensity Focused Ultrasound Keratoplasty on Rabbit Eyes. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109985
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109985