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Adjunct Intravitreous Triamcinolone Acetonide in the Treatment of Diabetic Macular Edema with Anti-VEGF Agents
Joint Authors
Carvounis, Petros E.
Garoon, Robert B.
Coffee, Robert E.
Jiang, Lai
Weng, Christina Y.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aims.
To compare visual and anatomic outcomes of adjunct intravitreous (IVT) triamcinolone acetonide to antivascular endothelial growth factor (VEGF) injections to IVT anti-VEGF injections alone for center-involving diabetic macular edema (DME) in treatment-naïve eyes.
Methods.
Retrospective study of treatment-naïve eyes with center-involving DME.
The primary outcome was the change in best corrected visual acuity (BCVA) in eyes receiving only IVT anti-VEGF (group 1) and eyes receiving IVT anti-VEGF and adjunct IVT-TA (group 2).
Results.
Included were 192 eyes.
The mean change in BCVA was +3.5 letters in group 1 compared to −3.5 letters in group 2 (p=0.048).
Final macular thickness improved by −94 μm in group 1 versus −68 μm in group 2 (p=0.26).
In group 1, 5/150 eyes compared to 9/42 eyes in group 2 (3.3% versus 21%, p=0.0005) had a IOP >10 mmHg increase.
Six of 126 phakic eyes in group 1 versus 12/33 phakic eyes in group 2 underwent cataract surgery (4.7% versus 36.3%, p=0.00009).
Conclusions.
IVT-TA results in no additional benefit in eyes treated with anti-VEGF agents for DME.
American Psychological Association (APA)
Garoon, Robert B.& Coffee, Robert E.& Jiang, Lai& Weng, Christina Y.& Carvounis, Petros E.. 2016. Adjunct Intravitreous Triamcinolone Acetonide in the Treatment of Diabetic Macular Edema with Anti-VEGF Agents. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109987
Modern Language Association (MLA)
Garoon, Robert B.…[et al.]. Adjunct Intravitreous Triamcinolone Acetonide in the Treatment of Diabetic Macular Edema with Anti-VEGF Agents. Journal of Ophthalmology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1109987
American Medical Association (AMA)
Garoon, Robert B.& Coffee, Robert E.& Jiang, Lai& Weng, Christina Y.& Carvounis, Petros E.. Adjunct Intravitreous Triamcinolone Acetonide in the Treatment of Diabetic Macular Edema with Anti-VEGF Agents. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109987
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109987