Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis
Joint Authors
Zhong, Yisheng
Huang, Shouyue
Lin, Zhongjing
Xie, Bing
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-19
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Purpose.
To investigate the potential relationship between open-angle glaucoma (OAG) and peripapillary choroidal thickness (PPCT).
Materials and Methods.
Relevant publications were searched systematically through various databases from inception to January 2016.
Studies comparing PPCT in OAG patients and healthy controls were retrieved.
All qualified articles were analyzed using Stata 14.0 and Revman 5.3 software.
Results.
A total of 13 studies were identified for inclusion.
There was a significant reduction of average PPCT in OAG patients compared to control participants (WMD = −24.07, 95% CI: −34.29, −13.85).
Reduction of PPCT was significant in the superior (WMD = −28.87, 95% CI: −44.96, −12.78) and nasal (WMD = −21.75, 95% CI: −41.52, −1.98) sectors, but there was no significant reduction of PPCT in the inferior (WMD = −9.57, 95% CI: −36.55, 17.40) and temporal (WMD = −13.85, 95% CI: −35.40, 7.70) sectors.
No obvious publication bias was detected.
Conclusions.
This meta-analysis suggests that open-angle glaucoma patients have significantly decreased peripapillary choroidal thickness compared to healthy individuals.
Peripapillary choroidal thickness measured by optical coherence tomography may be an important parameter to consider in open-angle glaucoma.
American Psychological Association (APA)
Lin, Zhongjing& Huang, Shouyue& Xie, Bing& Zhong, Yisheng. 2016. Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1109999
Modern Language Association (MLA)
Lin, Zhongjing…[et al.]. Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis. Journal of Ophthalmology No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1109999
American Medical Association (AMA)
Lin, Zhongjing& Huang, Shouyue& Xie, Bing& Zhong, Yisheng. Peripapillary Choroidal Thickness and Open-Angle Glaucoma: A Meta-Analysis. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1109999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1109999