The Application of OCTA in Assessment of Anti-VEGF Therapy for Idiopathic Choroidal Neovascularization
Joint Authors
Chen, Qin
Yu, Xiaobing
Sun, Zihan
Dai, Hong
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To assess the morphology of idiopathic choroidal neovascularization (ICNV) by optical coherence tomography angiography (OCTA) and determine the therapeutic effects of intravitreal antivascular endothelial growth factor (anti-VEGF).
Method.
Patients with naive ICNV were assessed by spectral domain optical coherence tomography (SD-OCT) and OCTA in this observational study.
The timing of observation was before treatment, 1 day after treatment with intravitreal anti-VEGF injection, and 1 month after the treatment.
The central retina thickness (CRT) on SD-OCT, selected CNV area, and flow area on OCTA were measured.
Results.
A total of 17 eyes from 17 patients with ICNV were included in this study.
OCTA showed visible irregular choroidal neovascularization with “tree-in-bud” form on outer retinal layer.
After treatment, as well as in the 1-day follow-up, CNV decreased in size from the periphery, and the vessel density was reduced.
As shown on OCTA, the selected CNV area and flow area were significantly reduced compared to pretreatment.
The rate of CNV vessel area changes was higher on OCTA than the changes in CRT on SD-OCT at 1-day and 1-month follow-up.
Conclusion.
Intravitreal injection of anti-VEGF is effective for idiopathic choroidal neovascularization, and the treatment outcomes are observable after 1 day.
OCTA provides a useful approach for monitoring and evaluating the treatment of intravitreal anti-VEGF for CNV.
American Psychological Association (APA)
Chen, Qin& Yu, Xiaobing& Sun, Zihan& Dai, Hong. 2016. The Application of OCTA in Assessment of Anti-VEGF Therapy for Idiopathic Choroidal Neovascularization. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110002
Modern Language Association (MLA)
Chen, Qin…[et al.]. The Application of OCTA in Assessment of Anti-VEGF Therapy for Idiopathic Choroidal Neovascularization. Journal of Ophthalmology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1110002
American Medical Association (AMA)
Chen, Qin& Yu, Xiaobing& Sun, Zihan& Dai, Hong. The Application of OCTA in Assessment of Anti-VEGF Therapy for Idiopathic Choroidal Neovascularization. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110002