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Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography
Joint Authors
Baudouin, Christophe
Labbé, Antoine
Lévêque, Pierre-Maxime
Zéboulon, Pierre
Brasnu, Emmanuelle
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).
Material and Method.
Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue).
The total ONH vessel density and temporal disc vessel density were measured.
Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients.
Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.
Results.
In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547; p < 0.0001 ) and 22.88% (0.364 versus 0.472; p = 0.001 ), respectively, as compared with the control group.
Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density ( r = 0.623 ; p < 0.0001 ) and total ONH vessel density ( r = 0.609 ; p < 0.0001 ).
Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.
Conclusion.
In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage.
OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.
American Psychological Association (APA)
Lévêque, Pierre-Maxime& Zéboulon, Pierre& Brasnu, Emmanuelle& Baudouin, Christophe& Labbé, Antoine. 2016. Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110039
Modern Language Association (MLA)
Lévêque, Pierre-Maxime…[et al.]. Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography. Journal of Ophthalmology No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1110039
American Medical Association (AMA)
Lévêque, Pierre-Maxime& Zéboulon, Pierre& Brasnu, Emmanuelle& Baudouin, Christophe& Labbé, Antoine. Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110039