Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population
Joint Authors
Safranow, Krzysztof
Wiszniewska, Barbara
Machalinska, Anna
Machalinski, Boguslaw
Zakrzewska, Aleksandra
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
The aim of this study was to investigate the relationships between MGL and ocular symptoms, several systemic conditions, and key markers of ocular surface health.
Methods.
We included into the study 91 healthy volunteers between the ages of 20 and 77 years.
We analyzed meibomian gland morphology, function, and lid margin alterations.
We correlated our findings with self-reported ocular symptoms, systemic medical history, lifestyle factors, and tear film abnormalities.
Results.
We observed that a high ocular surface disease index, a history of either chalazion or hordeolum, experience of puffy eyelids upon waking, and foreign body sensation all appeared to be predictors of an abnormal meiboscore after adjusting for age and sex (p=0.0007; p=0.001; p=0.02; p=0.001, resp.).
Multivariate logistic regression model including age and sex showed that there were three independent predictors of abnormal meiboscore: older age (OR = 1.03, 95% CI = 1.01–1.04 per year, p=0.006), postmenopausal hormone therapy (OR = 4.98, 95% CI = 1.52–16.30, p=0.007), and the use of antiallergy drugs (OR = 5.85, 95% CI = 2.18–15.72, p=0.0004).
Conclusion.
Our findings extend current knowledge on the pathophysiology of MGL.
American Psychological Association (APA)
Machalinska, Anna& Zakrzewska, Aleksandra& Safranow, Krzysztof& Wiszniewska, Barbara& Machalinski, Boguslaw. 2016. Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110063
Modern Language Association (MLA)
Machalinska, Anna…[et al.]. Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population. Journal of Ophthalmology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1110063
American Medical Association (AMA)
Machalinska, Anna& Zakrzewska, Aleksandra& Safranow, Krzysztof& Wiszniewska, Barbara& Machalinski, Boguslaw. Risk Factors and Symptoms of Meibomian Gland Loss in a Healthy Population. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110063
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110063