Effect of Phenylephrine on the Accommodative System
Joint Authors
Esteve-Taboada, José J.
Del Águila-Carrasco, Antonio J.
Bernal-Molina, Paula
Ferrer-Blasco, Teresa
López-Gil, Norberto
Montés-Micó, Robert
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-07
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Accommodation is controlled by the action of the ciliary muscle and mediated primarily by parasympathetic input through postganglionic fibers that originate from neurons in the ciliary and pterygopalatine ganglia.
During accommodation the pupil constricts to increase the depth of focus of the eye and improve retinal image quality.
Researchers have traditionally faced the challenge of measuring the accommodative properties of the eye through a small pupil and thus have relied on pharmacological agents to dilate the pupil.
Achieving pupil dilation (mydriasis) without affecting the accommodative ability of the eye (cycloplegia) could be useful in many clinical and research contexts.
Phenylephrine hydrochloride (PHCl) is a sympathomimetic agent that is used clinically to dilate the pupil.
Nevertheless, first investigations suggested some loss of functional accommodation in the human eye after PHCl instillation.
Subsequent studies, based on different measurement procedures, obtained contradictory conclusions, causing therefore an unexpected controversy that has been spread almost to the present days.
This manuscript reviews and summarizes the main research studies that have been performed to analyze the effect of PHCl on the accommodative system and provides clear conclusions that could help clinicians know the real effects of PHCl on the accommodative system of the human eye.
American Psychological Association (APA)
Esteve-Taboada, José J.& Del Águila-Carrasco, Antonio J.& Bernal-Molina, Paula& Ferrer-Blasco, Teresa& López-Gil, Norberto& Montés-Micó, Robert. 2016. Effect of Phenylephrine on the Accommodative System. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1110071
Modern Language Association (MLA)
Esteve-Taboada, José J.…[et al.]. Effect of Phenylephrine on the Accommodative System. Journal of Ophthalmology No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1110071
American Medical Association (AMA)
Esteve-Taboada, José J.& Del Águila-Carrasco, Antonio J.& Bernal-Molina, Paula& Ferrer-Blasco, Teresa& López-Gil, Norberto& Montés-Micó, Robert. Effect of Phenylephrine on the Accommodative System. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1110071
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110071