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Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery
Joint Authors
Lee, Jang Hoon
Song, In Seok
Kim, Kyoung Lae
Yoon, Sam Young
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate the effectiveness and optical quality of 3.0% topical diquafosol versus 0.05% cyclosporine A in dry eye patients following cataract surgery.
Methods.
In total, 40 eyes of 40 patients newly diagnosed with dry eye syndrome 1 week after cataract surgery were randomized to receive either 3.0% diquafosol ophthalmic solution six times daily or 0.05% cyclosporine A twice daily for 3 months.
Outcome measures were tear film break-up time (TBUT), results on Schirmer 1 test, ocular surface staining score, the ocular surface disease index (OSDI) score, and higher-order aberrations (HOAs).
Measurements were taken at baseline and at 1, 2, and 3 months.
Results.
In the diquafosol group, TBUT showed higher outcomes than the cyclosporine A group at 1 and 3 months.
Both groups showed increased scores on Schirmer 1 test.
The ocular surface staining score decreased in all periods in both groups.
Vertical coma and total HOAs decreased more in the cyclosporine A group than in the diquafosol group at 3 months.
Conclusion.
Both 3.0% diquafosol and 0.05% cyclosporine A were effective in treating dry eye after cataract surgery.
Diquafosol was more effective in increasing the tear secretion, but cyclosporine A was more effective in improving optical aberrations.
American Psychological Association (APA)
Lee, Jang Hoon& Song, In Seok& Kim, Kyoung Lae& Yoon, Sam Young. 2016. Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110077
Modern Language Association (MLA)
Lee, Jang Hoon…[et al.]. Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110077
American Medical Association (AMA)
Lee, Jang Hoon& Song, In Seok& Kim, Kyoung Lae& Yoon, Sam Young. Effectiveness and Optical Quality of Topical 3.0% Diquafosol versus 0.05% Cyclosporine A in Dry Eye Patients following Cataract Surgery. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110077
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110077