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Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone
Joint Authors
Fernández-Vega Sanz, Álvaro
Rangel, Carlos Mario
Villota Deleu, Eva
Fernández-Vega Sanz, Beatriz
Sánchez-Ávila, Ronald Mauricio
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Serous retinal detachment (SRD) is a common anatomical complication associated with dome-shaped macula (DSM) and staphyloma margin in myopic patients.
Here we described the anatomical and functional outcomes obtained with the use of oral spironolactone, a mineralocorticoid antagonist, in the management of myopic patients with SRD associated with DSM and staphyloma margin.
Methods.
We evaluated both eyes of twelve myopic patients with long-standing SRD associated with DSM or staphyloma margin.
The patients were treated daily for six months with oral spironolactone 50 mg.
Best-corrected visual acuity (BCVA) and central retinal thickness (CRT), determined by optical coherence tomography, were evaluated on the first day and on monthly follow-up visits.
Results.
Pretreatment BCVA (mean ± standard deviation) was 0.406 ± 0.324 LogMAR, and posttreatment BCVA was 0.421 ± 0.354 LogMAR (P=0.489).
Pretreatment CRT was 323.9 ± 78.6 μm, and after six months of treatment it was significantly lower, 291.2 ± 74.5 μm (P=0.010).
There were no treatment-related complications.
Conclusions.
We evaluated a novel treatment for SRD associated with DSM and staphyloma margin in myopic patients.
After six months of treatment with the mineralocorticoid antagonist spironolactone, the subretinal fluid and CRT were significantly reduced; however, there was no improvement in BCVA.
American Psychological Association (APA)
Fernández-Vega Sanz, Álvaro& Rangel, Carlos Mario& Villota Deleu, Eva& Fernández-Vega Sanz, Beatriz& Sánchez-Ávila, Ronald Mauricio. 2016. Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110095
Modern Language Association (MLA)
Fernández-Vega Sanz, Álvaro…[et al.]. Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone. Journal of Ophthalmology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110095
American Medical Association (AMA)
Fernández-Vega Sanz, Álvaro& Rangel, Carlos Mario& Villota Deleu, Eva& Fernández-Vega Sanz, Beatriz& Sánchez-Ávila, Ronald Mauricio. Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110095
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110095