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A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia
Joint Authors
Ni, Yang
Jiang, Bo
Ding, Zhihua
Li, Peng
Gu, Yangshun
Xu, Baisheng
Feng, Chunfei
Wu, Qin
Du, Chixin
Hong, Nan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The mouse model has been widely employed to explore the mysteries of myopia.
For now, existing techniques for induction of experimental myopia in mice can be classified into three types: (1) devices directly glued to the fur; (2) devices attached using a combination of glue and sutures; (3) devices attached using a skull-mounted apparatus.
These techniques each have its advantages, disadvantages when considering the devices stability, safety, complexity, effectiveness, and so forth.
Thus, techniques for myopia induction in mice have yet to be further refined to popularize the applications.
In this pilot study, we introduce a new head fixation device named the head-mounted spectacle frame apparatus for the study of mouse lens-induced myopia.
Surgical procedures for device attachment were relatively simple and easy to learn in our study.
Effective myopia induction was validated by retinoscopy refraction and axial length measurement using optical coherence tomography.
In addition, it showed improved compliance and reliable safety when compared to the published methods.
The head-mounted spectacle frame apparatus provides a new choice for the study of lens-induced myopia in mouse.
It also allows for the use of form deprivation, making it attractive for future experimental mouse myopia trials.
American Psychological Association (APA)
Gu, Yangshun& Xu, Baisheng& Feng, Chunfei& Ni, Yang& Wu, Qin& Du, Chixin…[et al.]. 2016. A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110097
Modern Language Association (MLA)
Gu, Yangshun…[et al.]. A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110097
American Medical Association (AMA)
Gu, Yangshun& Xu, Baisheng& Feng, Chunfei& Ni, Yang& Wu, Qin& Du, Chixin…[et al.]. A Head-Mounted Spectacle Frame for the Study of Mouse Lens-Induced Myopia. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110097
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110097