Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia
Joint Authors
Wang, Yan
Hou, Jie
Lei, Yulin
Zheng, Xiuyun
Zhang, Ying
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To evaluate the changes in epithelial thickness profile following transepithelial photorefractive keratectomy (T-PRK) for myopia and to investigate the effect of epithelial remodeling on corneal asphericity.
Methods.
Forty-four patients (44 right eyes) who underwent T-PRK were retrospectively evaluated.
Epithelial thickness was measured using spectral-domain optical coherence tomography at different corneal zones (central, 2 mm; paracentral, 2–5 mm; and mid-peripheral, 5-6 mm) preoperatively and at 1 week and 1, 3, and 6 months postoperatively.
The correlation between the changes in corneal epithelial thickness (ΔCET) and postoperative Q -value changes (ΔQ) was analyzed 6 months postoperatively.
Results.
Epithelial thickness at 6 months showed a negative meniscus-like lenticular pattern with less central thickening, which increased progressively toward the mid-periphery ( 3.69 ± 4.2 , 5.19 ± 3.8 , and 6.23 ± 3.9 μm at the center, paracenter, and mid-periphery, resp., P < 0.01 ).
A significant positive relationship was observed between epithelial thickening and ΔQ 6 months postoperatively ( r = 0.438 , 0.580, and 0.504, resp., P < 0.01 ).
Conclusions.
Significant epithelial thickening was observed after T-PRK and showed a lenticular change with more thickening mid-peripherally, resulting in increased oblateness postoperatively.
Epithelial remodeling may modify the epithelial thickness profile after surface ablation refractive surgery for myopia.
American Psychological Association (APA)
Hou, Jie& Wang, Yan& Lei, Yulin& Zheng, Xiuyun& Zhang, Ying. 2016. Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110101
Modern Language Association (MLA)
Hou, Jie…[et al.]. Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110101
American Medical Association (AMA)
Hou, Jie& Wang, Yan& Lei, Yulin& Zheng, Xiuyun& Zhang, Ying. Corneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110101
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110101