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Etiology and Clinical Characteristics of Single and Multiple Respiratory Virus Infections Diagnosed in Croatian Children in Two Respiratory Seasons
Joint Authors
Ljubin-Sternak, Sunčanica
Marijan, Tatjana
Ivković-Jureković, Irena
Čepin-Bogović, Jasna
Gagro, Alenka
Vraneš, Jasmina
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The aim of this study was to determine the causative agent of acute respiratory infection (ARI) in hospitalized children, as well as investigate the characteristics of ARIs with single and multiple virus detection in two respiratory seasons.
In 2010 and 2015, nasopharyngeal and pharyngeal swabs from a total of 134 children, admitted to the hospital due to ARI, were tested using multiplex PCR.
Viral etiology was established in 81.3% of the patients.
Coinfection with two viruses was diagnosed in 27.6% of the patients, and concurrent detection of three or more viruses was diagnosed in 12.8% of the patients.
The most commonly diagnosed virus in both seasons combined was respiratory syncytial virus (RSV) (28.6%), followed by parainfluenza viruses (PIVs) types 1–3 (18.4%), rhinovirus (HRV) (14.3%), human metapneumovirus (10.1%), adenovirus (AdV) (7.1%), influenza viruses types A and B (4.8%), and coronaviruses (4.2%).
In 2015, additional pathogens were investigated with the following detection rate: enterovirus (13.2%), bocavirus (HBoV) (10.5%), PIV-4 (2.6%), and parechovirus (1.3%).
There were no statistical differences between single and multiple virus infection regarding patients age, localization of infection, and severity of disease ( P > 0.05 ) .
AdV, HRV, HBoV, and PIVs were significantly more often detected in multiple virus infections compared to the other respiratory viruses ( P < 0.001 ) .
American Psychological Association (APA)
Ljubin-Sternak, Sunčanica& Marijan, Tatjana& Ivković-Jureković, Irena& Čepin-Bogović, Jasna& Gagro, Alenka& Vraneš, Jasmina. 2016. Etiology and Clinical Characteristics of Single and Multiple Respiratory Virus Infections Diagnosed in Croatian Children in Two Respiratory Seasons. Journal of Pathogens،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110200
Modern Language Association (MLA)
Ljubin-Sternak, Sunčanica…[et al.]. Etiology and Clinical Characteristics of Single and Multiple Respiratory Virus Infections Diagnosed in Croatian Children in Two Respiratory Seasons. Journal of Pathogens No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1110200
American Medical Association (AMA)
Ljubin-Sternak, Sunčanica& Marijan, Tatjana& Ivković-Jureković, Irena& Čepin-Bogović, Jasna& Gagro, Alenka& Vraneš, Jasmina. Etiology and Clinical Characteristics of Single and Multiple Respiratory Virus Infections Diagnosed in Croatian Children in Two Respiratory Seasons. Journal of Pathogens. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110200
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110200