Encephalitozoon cuniculi: Grading the Histological Lesions in Brain, Kidney, and Liver during Primoinfection Outbreak in Rabbits
Joint Authors
Nevárez-Garza, Alicia M.
Zarate-Ramos, Juan J.
Trejo-Chávez, Armando
Hernández-Martínez, Carlos A.
Castillo-Velázquez, Uziel
Rodríguez-Tovar, Luis E.
Hernández-Vidal, Gustavo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
This is the first confirmed report of Encephalitozoon cuniculi (E.
cuniculi) in farm meat rabbits located in Northern Mexico.
Eighty young rabbits exhibited clinical signs of this zoonotic emerging disease, like torticollis, ataxia, paresis, circling, and rolling.
Samples of brain, kidney, and liver were examined for histology lesions.
For the first time the lesions caused by E.
cuniculi were graded according to their severity (I, II, and III) and the size of the granulomas (Types A, B, and C).
The main cerebral injuries were Grade III, coinciding with the presence of Type C granulomas.
The cerebral lesions were located in the cortex, brain stem, and medulla.
The renal lesions were also Grade III distributed throughout cortex and renal medulla, with no granuloma formation.
The involvement of hypersensitivity Types III and IV is suggested.
All of the rabbits were seropositive to E.
cuniculi by CIA testing, suggesting that this zoonotic and emerging pathogen is widely distributed among animals intended for human consumption.
We believe this work could be used as a guide when examining E.
cuniculi and will provide direction to confirm the diagnosis of this pathogen.
American Psychological Association (APA)
Rodríguez-Tovar, Luis E.& Nevárez-Garza, Alicia M.& Trejo-Chávez, Armando& Hernández-Martínez, Carlos A.& Hernández-Vidal, Gustavo& Zarate-Ramos, Juan J.…[et al.]. 2016. Encephalitozoon cuniculi: Grading the Histological Lesions in Brain, Kidney, and Liver during Primoinfection Outbreak in Rabbits. Journal of Pathogens،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110212
Modern Language Association (MLA)
Rodríguez-Tovar, Luis E.…[et al.]. Encephalitozoon cuniculi: Grading the Histological Lesions in Brain, Kidney, and Liver during Primoinfection Outbreak in Rabbits. Journal of Pathogens No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1110212
American Medical Association (AMA)
Rodríguez-Tovar, Luis E.& Nevárez-Garza, Alicia M.& Trejo-Chávez, Armando& Hernández-Martínez, Carlos A.& Hernández-Vidal, Gustavo& Zarate-Ramos, Juan J.…[et al.]. Encephalitozoon cuniculi: Grading the Histological Lesions in Brain, Kidney, and Liver during Primoinfection Outbreak in Rabbits. Journal of Pathogens. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110212
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110212