![](/images/graphics-bg.png)
Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d’Ivoire versus Gabon
Joint Authors
Menan, Hervé
Yavo, William
Konaté, Abibatou
Kassi, Fulgence Kondo
Tshibola Mbuyi, Marie L.
Angora, Etienne Kpongbo
Mawili-Mboumba, Denise P.
Bouyou-Akotet, Marielle K.
Source
Journal of Parasitology Research
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
The characterization of genetic profile of Plasmodium isolates from different areas could help in better strategies for malaria elimination.
This study aimed to compare P.
falciparum diversity in two African countries.
Methods.
Isolates collected from 100 and 73 falciparum malaria infections in sites of Côte d’Ivoire (West Africa) and Gabon (Central Africa), respectively, were analyzed by a nested PCR amplification of msp1 and msp2 genes.
Results.
The K1 allelic family was widespread in Côte d’Ivoire (64.6%) and in Gabon (56.6%).
For msp2, the 3D7 alleles were more prevalent (>70% in both countries) compared to FC27 alleles.
In Côte d’Ivoire, the frequencies of multiple infections with msp1 (45.1%) and msp2 (40.3%) were higher than those found for isolates from Gabon, that is, 30.2% with msp1 and 31.4% with msp2.
The overall complexity of infection was 1.66 (SD = 0.79) in Côte d’Ivoire and 1.58 (SD = 0.83) in Gabon.
It decreased with age in Côte d’Ivoire in contrast to Gabon.
Conclusion.
Differences observed in some allelic families and in complexity profile may suggest an impact of epidemiological facies as well as immunological response on genetic variability of P.
falciparum.
American Psychological Association (APA)
Yavo, William& Konaté, Abibatou& Mawili-Mboumba, Denise P.& Kassi, Fulgence Kondo& Tshibola Mbuyi, Marie L.& Angora, Etienne Kpongbo…[et al.]. 2016. Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d’Ivoire versus Gabon. Journal of Parasitology Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110234
Modern Language Association (MLA)
Yavo, William…[et al.]. Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d’Ivoire versus Gabon. Journal of Parasitology Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110234
American Medical Association (AMA)
Yavo, William& Konaté, Abibatou& Mawili-Mboumba, Denise P.& Kassi, Fulgence Kondo& Tshibola Mbuyi, Marie L.& Angora, Etienne Kpongbo…[et al.]. Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d’Ivoire versus Gabon. Journal of Parasitology Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110234
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110234