Voltammetric Determination of Epinephrine in Pharmaceutical Sample with a Tyrosinase Nanobiosensor
Joint Authors
Alpat, Şenol
Özdemir, Kazım
Kılınç Alpat, Sibel
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
A novel carbon paste electrode modified with a multiwalled carbon nanotube (MWCNT), tyrosinase, and Nafion membrane (CP/MWCNT/Tyr/Nafion) was developed for voltammetric determination of epinephrine (EP).
The CP/MWCNT/Tyr/Nafion biosensor exhibited linear dynamic range from 5.0 × 10 - 6 M to 5.0 × 10 - 4 M EP concentration with a good correlation coefficient ( R 2 = 0.9985 ).
The detection limit of the biosensor was calculated as 3.0 × 10 - 7 M EP from the signal-to-noise ratio (S/N = 3).
Reproducibility of the biosensor was also calculated from relative standard deviation as 3.8% ( n = 5 ).
Ascorbic acid (AA) and uric acid (UA) did not interfere in the quantification of epinephrine.
The developed biosensor was also successfully applied for the determination of epinephrine in pharmaceutical sample.
The CP/MWCNT/Tyr/Nafion biosensor has good sensitivity, selectivity, stability, easy preparation procedure, and short analysis time and can be used for the determination of EP in pharmacological samples.
American Psychological Association (APA)
Alpat, Şenol& Özdemir, Kazım& Kılınç Alpat, Sibel. 2016. Voltammetric Determination of Epinephrine in Pharmaceutical Sample with a Tyrosinase Nanobiosensor. Journal of Sensors،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110515
Modern Language Association (MLA)
Alpat, Şenol…[et al.]. Voltammetric Determination of Epinephrine in Pharmaceutical Sample with a Tyrosinase Nanobiosensor. Journal of Sensors No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1110515
American Medical Association (AMA)
Alpat, Şenol& Özdemir, Kazım& Kılınç Alpat, Sibel. Voltammetric Determination of Epinephrine in Pharmaceutical Sample with a Tyrosinase Nanobiosensor. Journal of Sensors. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110515
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110515