Is There a Relationship between the Stratum Corneum Thickness and That of the Viable Parts of Tumour Cells in Basal Cell Carcinoma?
Joint Authors
Christensen, Eidi
Foss, Olav Andreas
Mjønes, Patricia
Fismen, Silje
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Basal cell carcinoma (BCC) is an invasive epithelial skin tumour.
The thickness of the outermost epidermal layer of the skin, the stratum corneum (SC), influences drug uptake and penetration into tumour and may thereby affect the response of BCC to topical treatment.
The aim was to investigate a possible relationship between the thickness of the SC and that of the viable part of BCC.
Histopathological evaluations of the corresponding SC and viable tumour thickness measurements of individual BCCs of different subtypes were explored.
A total of 53 BCCs from 46 patients were studied.
The median tumour thickness was 1.7 mm (0.8–3.0 mm), with a significant difference between subtypes (p<0.001).
The SC had a median thickness of 0.3 mm (0.2–0.4 mm), with no difference between tumour subtypes (p=0.415).
Additionally, no significant association between the thickness of the SC and that of the viable part of the tumour was demonstrated (p=0.381).
In conclusion our results indicate that SC thickness is relatively constant in BCC.
American Psychological Association (APA)
Foss, Olav Andreas& Mjønes, Patricia& Fismen, Silje& Christensen, Eidi. 2016. Is There a Relationship between the Stratum Corneum Thickness and That of the Viable Parts of Tumour Cells in Basal Cell Carcinoma?. Journal of Skin Cancer،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110736
Modern Language Association (MLA)
Foss, Olav Andreas…[et al.]. Is There a Relationship between the Stratum Corneum Thickness and That of the Viable Parts of Tumour Cells in Basal Cell Carcinoma?. Journal of Skin Cancer No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1110736
American Medical Association (AMA)
Foss, Olav Andreas& Mjønes, Patricia& Fismen, Silje& Christensen, Eidi. Is There a Relationship between the Stratum Corneum Thickness and That of the Viable Parts of Tumour Cells in Basal Cell Carcinoma?. Journal of Skin Cancer. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110736
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110736