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Plasma Cytokine Profiles in Long-Term Strenuous Exercise
Joint Authors
Lyberg, Torstein
Nielsen, Hilde G.
Øktedalen, Olav
Opstad, Per-Kristian
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The open window theory indicates altered immunity 3 to 72 hours after exercise.
The J-curve describes the risk of illness in response to exercise.
The aim of this study was to examine the secretion of proinflammatory and anti-inflammatory cytokines before and after long-term strenuous exercise.
Fourteen marathon and 16 half-marathon runners and 10 military cadets participating in a military ranger-training course were recruited to this study.
Within-subject design was used measuring levels of plasma cytokines before, during, and after exercise.
Plasma cytokines were measured using Luminex multiplex technology and ELISA.
Comparing pre/post plasma levels both the marathon- and the half-marathon runners showed heavily increased levels of IL-6, IL-10, and IL-8 ( P < 0.001 ).
LPS stimulation among the half-marathon runners decreased the postrace levels of IL-6, IL-1b, and TNFα by 45%, 24%, and 43%, respectively ( P < 0.01 ).
During the ranger training course the spontaneous and LPS-stimulated levels of IL-6, IL-8, IL-10, IL-1b, and TNFα changed in a similar fashion as in the half-marathon runners although the fluctuations were smaller.
Our study supports the open window and the J-curve theory; the immune system is more activated and the subjects are more threatened to infectious pathogens after intensive physical activity and in the period after exercise.
American Psychological Association (APA)
Nielsen, Hilde G.& Øktedalen, Olav& Opstad, Per-Kristian& Lyberg, Torstein. 2016. Plasma Cytokine Profiles in Long-Term Strenuous Exercise. Journal of Sports Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110746
Modern Language Association (MLA)
Nielsen, Hilde G.…[et al.]. Plasma Cytokine Profiles in Long-Term Strenuous Exercise. Journal of Sports Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110746
American Medical Association (AMA)
Nielsen, Hilde G.& Øktedalen, Olav& Opstad, Per-Kristian& Lyberg, Torstein. Plasma Cytokine Profiles in Long-Term Strenuous Exercise. Journal of Sports Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110746