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Microcystin-LR Induced Immunotoxicity in Mammals
Joint Authors
Lone, Yaqoob
Bhide, Mangla
Koiri, Raj Kumar
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication.
Exposure to microcystins is a global health problem because of its association with various other pathological effects and people all over the world are exposed to microcystins on a regular basis.
Evidence shows that microcystin-LR (MC-LR) may adversely affect the immune system, but its specific effects on immune functions are lacking.
In the present review, immunotoxicological effects associated with MC-LR in animals, humans, and in vitro models have been reported.
Overall, the data shows that chronic exposure to MC-LR has the potential to impair vital immune responses which could lead to increased risk of various diseases including cancers.
Studies in animal and in vitro models have provided some pivotal understanding into the potential mechanisms of MC-LR related immunotoxicity suggesting that further investigation, particularly in humans, is required to better understand the relationship between development of disease and the MC-LR exposure.
American Psychological Association (APA)
Lone, Yaqoob& Bhide, Mangla& Koiri, Raj Kumar. 2016. Microcystin-LR Induced Immunotoxicity in Mammals. Journal of Toxicology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110833
Modern Language Association (MLA)
Lone, Yaqoob…[et al.]. Microcystin-LR Induced Immunotoxicity in Mammals. Journal of Toxicology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1110833
American Medical Association (AMA)
Lone, Yaqoob& Bhide, Mangla& Koiri, Raj Kumar. Microcystin-LR Induced Immunotoxicity in Mammals. Journal of Toxicology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110833
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110833