Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria
Joint Authors
John-Olabode, Sarah
Adediran, Adewumi
Uche, Ebele
Dosunmu, Adedoyin
Akinbami, A. Akinsegun
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-21
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
This study sought to identify the pattern of electrocardiographic changes in steady state adult sickle cell anaemia.
Methods.
A case-control, cross-sectional study was conducted amongst sickle cell patients attending the sickle cell clinic of Lagos State University Teaching Hospital, Ikeja, and HbAA controls.
All consenting participants had haemoglobin electrophoresis done and were subjected to electrocardiography (ECG).
The descriptive data were given as means ± standard deviation (SD).
The differences were considered to be statistically significant when the p value obtained was <0.05.
Results.
A total of ninety-three sickle cell anaemia (SCA) patients and ninety haemoglobin AA (controls) were enrolled.
There was no significant difference in the age of the participants with SCA and that of the controls but the body mass index was significantly higher in controls ( p = 0.0001 ).
Overall, 73.1% (68 of 93) had abnormal ECG while only 2 of 90 (2.2%) of controls had abnormal ECG.
The common abnormalities observed were left ventricular hypertrophy, biventricular hypertrophy, and right ventricular hypertrophy.
Conclusion.
Patients with SCA in steady state tend to have normal heart rate but about 50% of them would have had ECG changes before the age of 20 years.
ECG being a noninvasive test may be used to identify patients at risk for early intervention.
American Psychological Association (APA)
Dosunmu, Adedoyin& Akinbami, A. Akinsegun& Uche, Ebele& Adediran, Adewumi& John-Olabode, Sarah. 2016. Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria. Journal of Tropical Medicine،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110849
Modern Language Association (MLA)
Dosunmu, Adedoyin…[et al.]. Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria. Journal of Tropical Medicine No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1110849
American Medical Association (AMA)
Dosunmu, Adedoyin& Akinbami, A. Akinsegun& Uche, Ebele& Adediran, Adewumi& John-Olabode, Sarah. Electrocardiographic Study in Adult Homozygous Sickle Cell Disease Patients in Lagos, Nigeria. Journal of Tropical Medicine. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110849
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110849