![](/images/graphics-bg.png)
Predictors of Regional Lymph Node Recurrence after Initial Thyroidectomy in Patients with Thyroid Cancer
Joint Authors
Sharifi, Amirsina
Shojaeifard, Abolfazl
Soroush, Ahmadreza
Jafari, Mehdi
Abdehgah, Ali Ghorbani
Mahmoudzade, Hossein
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Regional lymph node recurrence (RLNR) is common in patients with thyroid cancer but clinicopathological predictors are unclear.
We aimed to clarify these predictors and identify patients who would benefit from prophylactic lymph node dissection the most.
Method.
343 patients with different types of thyroid cancer were analyzed retrospectively.
All patients underwent total thyroidectomy between 2007 and 2013.
Results.
The median ± interquartile range of patients’ age was 40 ± 25 years.
245 (71.4%) patients were female.
Regarding the risk of regional lymph node recurrence, we found that male gender, age ≥45 years, non-PTC (i.e., medullary, follicular, and anaplastic types) histopathology, T3 (i.e., tumor size >4 cm in the greatest dimension limited to the thyroid or any tumor with minimal extrathyroid extension), stage IVa, and isolated cervical lymphadenopathy as initial manifestation (ICL) are significant risk factors.
T3 (p < 0.001; odds ratio = 156.41, 95% CI [55.72–439.1]) and ICL (p < 0.001; odds ratio = 77.79, 95% CI [31.55–191.81]) were the strongest predictors of regional lymph node recurrence.
Conclusion.
We found easily achievable risk factors for RLNR in thyroid cancers patients.
We suggested that patients with specific clinicopathological features like male gender, age ≥45 years, larger tumor size, and extrathyroidal extension be considered as prophylactic lymphadenectomy candidates.
American Psychological Association (APA)
Sharifi, Amirsina& Shojaeifard, Abolfazl& Soroush, Ahmadreza& Jafari, Mehdi& Abdehgah, Ali Ghorbani& Mahmoudzade, Hossein. 2016. Predictors of Regional Lymph Node Recurrence after Initial Thyroidectomy in Patients with Thyroid Cancer. Journal of Thyroid Research،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110877
Modern Language Association (MLA)
Sharifi, Amirsina…[et al.]. Predictors of Regional Lymph Node Recurrence after Initial Thyroidectomy in Patients with Thyroid Cancer. Journal of Thyroid Research No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1110877
American Medical Association (AMA)
Sharifi, Amirsina& Shojaeifard, Abolfazl& Soroush, Ahmadreza& Jafari, Mehdi& Abdehgah, Ali Ghorbani& Mahmoudzade, Hossein. Predictors of Regional Lymph Node Recurrence after Initial Thyroidectomy in Patients with Thyroid Cancer. Journal of Thyroid Research. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110877
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110877