Epidermal Growth Factor and Intestinal Barrier Function
Joint Authors
Tang, Xiaopeng
Liu, Hu
Yang, Shufen
Li, Zuohua
Zhong, Jinfeng
Fang, Rejun
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Epidermal growth factor (EGF) is a 53-amino acid peptide that plays an important role in regulating cell growth, survival, migration, apoptosis, proliferation, and differentiation.
In addition, EGF has been established to be an effective intestinal regulator helping to protect intestinal barrier integrity, which was essential for the absorption of nutrients and health in humans and animals.
Several researches have demonstrated that EGF via binding to the EGF receptor and subsequent activation of Ras/MAPK, PI3K/AKT, PLC-γ/PKC, and STATS signal pathways regulates intestinal barrier function.
In this review, the relationship between epidermal growth factor and intestinal development and intestinal barrier is described, to provide a better understanding of the effects of EGF on intestine development and health.
American Psychological Association (APA)
Tang, Xiaopeng& Liu, Hu& Yang, Shufen& Li, Zuohua& Zhong, Jinfeng& Fang, Rejun. 2016. Epidermal Growth Factor and Intestinal Barrier Function. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110951
Modern Language Association (MLA)
Tang, Xiaopeng…[et al.]. Epidermal Growth Factor and Intestinal Barrier Function. Mediators of Inflammation No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1110951
American Medical Association (AMA)
Tang, Xiaopeng& Liu, Hu& Yang, Shufen& Li, Zuohua& Zhong, Jinfeng& Fang, Rejun. Epidermal Growth Factor and Intestinal Barrier Function. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1110951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110951