Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma
Joint Authors
Gibson, Peter G.
Xiong, Lingxin
Wang, Fang
Lu, Yanjiao
Wang, Guoqiang
Wang, Ting
Dong, Zhiyong
Zhang, Weijie
Li, Hui
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Inflammation is a complex biological response to detrimental stimuli and can be a double-edged sword.
Inflammation plays a protective role in removing pathogenic factors, but dysregulated inflammation is associated with several major fatal diseases such as asthma, cancer, and cardiovascular diseases.
Asthma is a complex heterogenous disease caused by genetic and environmental factors.
TLRs are the primary proteins associated with the innate and adaptive immune responses to these fatal factors and play an important role in recognizing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), which initiates the downstream immune response.
Due to the complex TLRs cascade and nowadays unsuccessful control in asthma, new studies are focused on TLRs and other potential targets in TLR cascade to minimize airway inflammation.
American Psychological Association (APA)
Dong, Zhiyong& Xiong, Lingxin& Zhang, Weijie& Gibson, Peter G.& Wang, Ting& Lu, Yanjiao…[et al.]. 2016. Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110961
Modern Language Association (MLA)
Dong, Zhiyong…[et al.]. Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma. Mediators of Inflammation No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1110961
American Medical Association (AMA)
Dong, Zhiyong& Xiong, Lingxin& Zhang, Weijie& Gibson, Peter G.& Wang, Ting& Lu, Yanjiao…[et al.]. Holding the Inflammatory System in Check: TLRs and Their Targeted Therapy in Asthma. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110961
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110961