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Serum Cytokinome Profile Evaluation: A Tool to Define New Diagnostic and Prognostic Markers of Cancer Using Multiplexed Bead-Based Immunoassays
Joint Authors
Ciliberto, Gennaro
Capone, Francesca
Guerriero, Eliana
Sorice, Angela
Colonna, Giovanni
Costantini, Susan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
In recent years, many researchers are focusing their attention on the link between inflammation and cancer.
The inflammation is involved in the tumor development and suppression, by stimulating the immune response.
In particular, the transition from chronic inflammation to cancer produces angiogenic and growth factors able to repair the tissue and to promote cancer cell survival, implantation, and growth.
In this contest, the cytokines contribute to the development of these processes becoming active before and during the inflammatory process and playing an important function at the various disease levels.
Thus, these proteins can represent specific markers of tumor development and progression.
Therefore the “cytokinome” term is used to indicate the evaluation of cytokine pattern by using an “omics” approach.
Newly, specific protein chips of considerable and improved sensitivity are being developed to determine simultaneously several and different cytokines.
This can be achieved by a multiplex technology that, through the use of small amounts of serum or other fluids, is used to determine the presence and the levels of underrepresented cytokines.
Since this method is an accurate, sensitive, and reproducible cytokine assay, it is already used in many different studies.
Thus, this review focuses on the more latest aspects related to cytokinome profile evaluation in different cancers.
American Psychological Association (APA)
Capone, Francesca& Guerriero, Eliana& Sorice, Angela& Colonna, Giovanni& Ciliberto, Gennaro& Costantini, Susan. 2016. Serum Cytokinome Profile Evaluation: A Tool to Define New Diagnostic and Prognostic Markers of Cancer Using Multiplexed Bead-Based Immunoassays. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1110994
Modern Language Association (MLA)
Capone, Francesca…[et al.]. Serum Cytokinome Profile Evaluation: A Tool to Define New Diagnostic and Prognostic Markers of Cancer Using Multiplexed Bead-Based Immunoassays. Mediators of Inflammation No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1110994
American Medical Association (AMA)
Capone, Francesca& Guerriero, Eliana& Sorice, Angela& Colonna, Giovanni& Ciliberto, Gennaro& Costantini, Susan. Serum Cytokinome Profile Evaluation: A Tool to Define New Diagnostic and Prognostic Markers of Cancer Using Multiplexed Bead-Based Immunoassays. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1110994
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1110994