Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells
Author
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Dendritic cells present in the digestive tract are constantly exposed to environmental antigens, commensal flora, and invading pathogens.
Under steady-state conditions, these cells have high tolerogenic potential, triggering differentiation of regulatory T cells to protect the host from unwanted proinflammatory immune responses to innocuous antigens or commensals.
On the other hand, these cells must discriminate between commensal flora and invading pathogens and mount powerful immune response against pathogens.
A potential result of unbalanced tolerogenic versus proinflammatory responses mediated by dendritic cells is associated with chronic inflammatory conditions, such as Crohn’s disease, ulcerative colitis, food allergies, and celiac disease.
Herein, we review the dendritic cell population involved in mediating tolerance and immunity in mucosal surfaces, the progress in unveiling their development in vivo, and factors that can influence their functions.
American Psychological Association (APA)
Aliberti, J.. 2016. Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111000
Modern Language Association (MLA)
Aliberti, J.. Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells. Mediators of Inflammation No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1111000
American Medical Association (AMA)
Aliberti, J.. Immunity and Tolerance Induced by Intestinal Mucosal Dendritic Cells. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111000
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111000