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Celecoxib Adjunctive Treatment to Antipsychotics in Schizophrenia: A Review of Randomized Clinical Add-On Trials
Joint Authors
Fornaro, Michele
Marini, Stefano
De Berardis, Domenico
Vellante, Federica
Orsolini, Laura
Girinelli, Gabriella
Carano, Alessandro
Gambi, Francesco
Martinotti, Giovanni
di Giannantonio, Massimo
Santacroce, Rita
Valchera, Alessandro
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Schizophrenia is a severe, chronic and debilitating mental disorder.
Past literature has reported various hypotheses about the psychopathology of schizophrenia.
Recently, a growing literature has been trying to explain the role of inflammation in the etiopathogenesis of schizophrenia.
In the past, numerous immune modulation and anti-inflammatory treatment options have been proposed for schizophrenia, but sometimes the results were inconsistent.
Electronic search was carried out in November 2015.
PubMed and Scopus databases have been used to find studies to introduce in this review.
Only randomized-placebo-controlled add-on trials were taken into account.
In this way, six articles were obtained for the discussion.
Celecoxib showed beneficial effects mostly in early stages of schizophrenia.
In chronic schizophrenia, the data are controversial, possibly in part for methodological reasons.
American Psychological Association (APA)
Marini, Stefano& De Berardis, Domenico& Vellante, Federica& Santacroce, Rita& Orsolini, Laura& Valchera, Alessandro…[et al.]. 2016. Celecoxib Adjunctive Treatment to Antipsychotics in Schizophrenia: A Review of Randomized Clinical Add-On Trials. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111011
Modern Language Association (MLA)
Marini, Stefano…[et al.]. Celecoxib Adjunctive Treatment to Antipsychotics in Schizophrenia: A Review of Randomized Clinical Add-On Trials. Mediators of Inflammation No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1111011
American Medical Association (AMA)
Marini, Stefano& De Berardis, Domenico& Vellante, Federica& Santacroce, Rita& Orsolini, Laura& Valchera, Alessandro…[et al.]. Celecoxib Adjunctive Treatment to Antipsychotics in Schizophrenia: A Review of Randomized Clinical Add-On Trials. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111011
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111011