Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces
Joint Authors
Riboni, Laura
Abdel Hadi, Loubna
Di Vito, Clara
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Complex sphingolipids are essential structural components of intestinal membranes, providing protection and integrity to the intestinal mucosa and regulating intestinal absorption processes.
The role of sphingolipid signaling has been established in numerous cellular events, including intestinal cell survival, growth, differentiation, and apoptosis.
A significant body of knowledge demonstrates that intestinal sphingolipids play a crucial role, as such and through their signaling pathways, in immunity and inflammatory disorders.
In this review, we report on and discuss the current knowledge on the metabolism, signaling, and functional implications of sphingolipids in inflammatory bowel disease (IBD), focusing on the different aspects of sphingolipid actions on inflammatory responses and on the potential of sphingolipid-targeted molecules as anti-IBD therapeutic agents.
American Psychological Association (APA)
Abdel Hadi, Loubna& Di Vito, Clara& Riboni, Laura. 2016. Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1111036
Modern Language Association (MLA)
Abdel Hadi, Loubna…[et al.]. Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces. Mediators of Inflammation No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1111036
American Medical Association (AMA)
Abdel Hadi, Loubna& Di Vito, Clara& Riboni, Laura. Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1111036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111036