Effects of Glutamate and Aspartate on Serum Antioxidative Enzyme, Sex Hormones, and Genital Inflammation in Boars Challenged with Hydrogen Peroxide
Joint Authors
Ni, Hengjia
Lu, Lu
Deng, Jinpin
Fan, Wenjun
Yao, Jiming
Li, T. J.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-29
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Oxidative stress is associated with infertility.
This study was conducted to determine the effects of glutamate and aspartate on serum antioxidative enzymes, sex hormones, and genital inflammation in boars suffering from oxidative stress.
Methods.
Boars were randomly divided into 4 groups: the nonchallenged control (CON) and H2O2-challenged control (BD) groups were fed a basal diet supplemented with 2% alanine; the other two groups were fed the basal diet supplemented with 2% glutamate (GLU) or 2% aspartate (ASP).
The BD, GLU, and ASP groups were injected with hydrogen peroxide (H2O2) on day 15.
The CON group was injected with 0.9% sodium chloride solution on the same day.
Results.
Dietary aspartate decreased the malondialdehyde (MDA) level in serum ( P < 0.05 ) compared with the BD group.
Additionally, aspartate maintained serum luteinizing hormone (LH) at a relatively stable level.
Moreover, glutamate and aspartate increased transforming growth factor-β1 (TGF-β1) and interleukin-10 (IL-10) levels in the epididymis and testis ( P < 0.05 ) compared with the BD group.
Conclusion.
Both glutamate and aspartate promoted genital mRNA expressions of anti-inflammatory factors after oxidative stress.
Aspartate more effectively decreased serum MDA and prevented fluctuations in serum sex hormones after H2O2 challenge than did glutamate.
American Psychological Association (APA)
Ni, Hengjia& Lu, Lu& Deng, Jinpin& Fan, Wenjun& Li, T. J.& Yao, Jiming. 2016. Effects of Glutamate and Aspartate on Serum Antioxidative Enzyme, Sex Hormones, and Genital Inflammation in Boars Challenged with Hydrogen Peroxide. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1111066
Modern Language Association (MLA)
Ni, Hengjia…[et al.]. Effects of Glutamate and Aspartate on Serum Antioxidative Enzyme, Sex Hormones, and Genital Inflammation in Boars Challenged with Hydrogen Peroxide. Mediators of Inflammation No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1111066
American Medical Association (AMA)
Ni, Hengjia& Lu, Lu& Deng, Jinpin& Fan, Wenjun& Li, T. J.& Yao, Jiming. Effects of Glutamate and Aspartate on Serum Antioxidative Enzyme, Sex Hormones, and Genital Inflammation in Boars Challenged with Hydrogen Peroxide. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1111066
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111066