Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair
Joint Authors
Meschi, Tiziana
Ambrosoli, Andrea Luigi
Cappelleri, Gianluca
Saccani Jotti, Gloria MR
Fanelli, Guido
Allegri, Massimo
Lavand'homme, Patricia
Bugada, Dario
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Poor acute pain control and inflammation are important risk factors for Persistent Postsurgical Pain (PPSP).
The aim of the study is to investigate, in the context of a prospective cohort of patients undergoing hernia repair, potential risk factors for PPSP.
Data about BMI, anxious-depressive disorders, neutrophil-tolymphocyte ratio (NLR), proinflammatory medical comorbidities were collected.
An analysis for correlation between comorbidities and PPSP was performed in those patients experiencing chronic pain at 3 months after surgery.
Tramadol resulted less effective in pain at movement in patients with a proinflammatory status.
Preoperative hypertension and NLR > 4 were correlated with PPSP intensity.
Regional anesthesia was significantly protective on PPSP when associated with ketorolac.
Patients with pain at 1 month were significantly more prone to develop PPSP at 3 months.
NSAIDs or weak opioids are equally effective on acute pain and on PPSP development after IHR, but Ketorolac has better profile in patients with inflammatory background or undergoing regional anesthesia.
Drug choice should be based on their potential side effects, patient’s profile (comorbidities, preoperative inflammation, and hypertension), and type of anesthesia.
Close monitoring is necessary to early detect pain conditions more prone to progress to a chronic syndrome.
American Psychological Association (APA)
Bugada, Dario& Lavand'homme, Patricia& Ambrosoli, Andrea Luigi& Cappelleri, Gianluca& Saccani Jotti, Gloria MR& Meschi, Tiziana…[et al.]. 2016. Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111126
Modern Language Association (MLA)
Bugada, Dario…[et al.]. Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair. Mediators of Inflammation No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1111126
American Medical Association (AMA)
Bugada, Dario& Lavand'homme, Patricia& Ambrosoli, Andrea Luigi& Cappelleri, Gianluca& Saccani Jotti, Gloria MR& Meschi, Tiziana…[et al.]. Effect of Preoperative Inflammatory Status and Comorbidities on Pain Resolution and Persistent Postsurgical Pain after Inguinal Hernia Repair. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111126
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111126