The Effect of Immunonutrition on the Postoperative Complications in Thymoma with Myasthenia Gravis
Joint Authors
Xin, Yanzhong
Cui, Youbin
Cai, Hongfei
Wu, Lihui
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Object.
To test whether preoperative immunonutrition is efficacious in reducing postoperative complications in patients of thymoma with myasthenia gravis (MG).
Material and Methods.
A total of 244 patients operated on for thymoma with myasthenia gravis were prospectively assigned to two groups, each receiving seven-day preoperative and seven-day postoperative nutrition.
The patients in immunonutrition group were given oral immunonutrition (IN).
The patients in control group received oral standard nutrition.
Immunonutritional and inflammatory biomarkers (IgA, IgG, IgM, CD3t, CD4t, CD8t, CD4t/CD8t ratio, NK-cell, prealbumin, albumin, white blood cells counts, and C-reactive protein) and clinical variables (age, gender, BMI, performance status, type of thymoma, type of MG, operative time, pathology, operative approach, postoperative complications, quantity of drainage, hospital stays) were examined.
Results.
A significant reduction in the length of hospital stay, quantity of drainage, and postoperative complications was observed in the IN group (p<0.05).
An increase in the level of IgA, IgG, IgM, CD3+T, CD4+T, CD4+T/CD8+T, WBC, CRP, and NK-cell in the IN group was observed after thymectomy, while a decrease was seen with regard to prealbumin and albumin (p<0.05).
Conclusion.
Preoperative immunonutrition support is effective in reducing postoperative complications in patients of thymoma with MG.
It helps to lower the risk of postoperative infectious complications and hospital stays.
American Psychological Association (APA)
Xin, Yanzhong& Cai, Hongfei& Wu, Lihui& Cui, Youbin. 2016. The Effect of Immunonutrition on the Postoperative Complications in Thymoma with Myasthenia Gravis. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111274
Modern Language Association (MLA)
Xin, Yanzhong…[et al.]. The Effect of Immunonutrition on the Postoperative Complications in Thymoma with Myasthenia Gravis. Mediators of Inflammation No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1111274
American Medical Association (AMA)
Xin, Yanzhong& Cai, Hongfei& Wu, Lihui& Cui, Youbin. The Effect of Immunonutrition on the Postoperative Complications in Thymoma with Myasthenia Gravis. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1111274
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111274