Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (Eugenol) on Inflammatory and Apoptosis Processes in Dental Pulp Fibroblasts
Joint Authors
Ruiz-Rodriguez, M. Socorro
Garrocho-Rangel, Arturo
Escobar-García, Diana María
Martínez-Herrera, Andrea
Vértiz-Hernández, Antonio
Pozos-Guillen, Amaury
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Eugenol (mixed with zinc oxide powder) is widely used as direct capping material during pulp therapy in primary teeth.
The aim of the present study was to evaluate the effect of eugenol on diverse genes involved in inflammatory and cell apoptosis processes.
The regulatory effect of eugenol on the expression of inflammation and apoptotic genes was evaluated in dental pulp fibroblasts from extracted third molars, cultured under concentration of eugenol of 13 μM.
Eugenol allowed the expression of inflammatory and apoptotic genes when compared with positive and negative controls.
Eugenol is a proinflammatory agent when it is in direct contact with healthy tissues and behaves as an anti-inflammatory agent in tissues undergoing inflammatory/apoptotic processes, as in cases of pulp inflammation in primary teeth.
These findings are relevant for dentistry, when considering the application of safer pulp treatments to grossly carious children’s teeth.
American Psychological Association (APA)
Martínez-Herrera, Andrea& Pozos-Guillen, Amaury& Ruiz-Rodriguez, M. Socorro& Garrocho-Rangel, Arturo& Vértiz-Hernández, Antonio& Escobar-García, Diana María. 2016. Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (Eugenol) on Inflammatory and Apoptosis Processes in Dental Pulp Fibroblasts. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111298
Modern Language Association (MLA)
Martínez-Herrera, Andrea…[et al.]. Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (Eugenol) on Inflammatory and Apoptosis Processes in Dental Pulp Fibroblasts. Mediators of Inflammation No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1111298
American Medical Association (AMA)
Martínez-Herrera, Andrea& Pozos-Guillen, Amaury& Ruiz-Rodriguez, M. Socorro& Garrocho-Rangel, Arturo& Vértiz-Hernández, Antonio& Escobar-García, Diana María. Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (Eugenol) on Inflammatory and Apoptosis Processes in Dental Pulp Fibroblasts. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1111298