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Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity
Joint Authors
Munoz, Pablo
Ramírez-Barrantes, R.
Cordova, C.
Poblete, H.
Marchant, I.
Wianny, F.
Olivero, P.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-05
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The development of new strategies to renew and repair neuronal networks using neural plasticity induced by stem cell graft could enable new therapies to cure diseases that were considered lethal until now.
In adequate microenvironment a neuronal progenitor must receive molecular signal of a specific cellular context to determine fate, differentiation, and location.
TRPV1, a nonselective calcium channel, is expressed in neurogenic regions of the brain like the subgranular zone of the hippocampal dentate gyrus and the telencephalic subventricular zone, being valuable for neural differentiation and neural plasticity.
Current data show that TRPV1 is involved in several neuronal functions as cytoskeleton dynamics, cell migration, survival, and regeneration of injured neurons, incorporating several stimuli in neurogenesis and network integration.
The function of TRPV1 in the brain is under intensive investigation, due to multiple places where it has been detected and its sensitivity for different chemical and physical agonists, and a new role of TRPV1 in brain function is now emerging as a molecular tool for survival and control of neural stem cells.
American Psychological Association (APA)
Ramírez-Barrantes, R.& Cordova, C.& Poblete, H.& Munoz, Pablo& Marchant, I.& Wianny, F.…[et al.]. 2016. Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity. Neural Plasticity،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1112976
Modern Language Association (MLA)
Ramírez-Barrantes, R.…[et al.]. Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity. Neural Plasticity No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1112976
American Medical Association (AMA)
Ramírez-Barrantes, R.& Cordova, C.& Poblete, H.& Munoz, Pablo& Marchant, I.& Wianny, F.…[et al.]. Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1112976
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1112976