Training-Induced Functional Gains following SCI
Joint Authors
Ward, P. Jillian
Herrity, A. N.
Harkema, S. J.
Hubscher, C. H.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-15
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
We previously demonstrated that daily, hour-long training sessions significantly improved both locomotor (limb kinematics, gait, and hindlimb flexor-extensor bursting patterns) and nonlocomotor (bladder function and at-level mechanical allodynia) functions following a moderate contusive spinal cord injury.
The amount of training needed to achieve this recovery is unknown.
Furthermore, whether this recovery is induced primarily by neuronal activity below the lesion or other aspects related to general exercise is unclear.
Therefore, the current study objectives were to (1) test the efficacy of 30 minutes of step training for recovery following a clinically relevant contusion injury in male Wistar rats and (2) test the efficacy of training without hindlimb engagement.
The results indicate that as little as 30 minutes of step training six days per week enhances overground locomotion in male rats with contusive spinal cord injury but does not alter allodynia or bladder function.
Thirty minutes of forelimb-only exercise did not alter locomotion, allodynia, or bladder function, and neither training protocol altered the amount of in-cage activity.
Taken together, locomotor improvements were facilitated by hindlimb step training for 30 minutes, but longer durations of training are required to affect nonlocomotor systems.
American Psychological Association (APA)
Ward, P. Jillian& Herrity, A. N.& Harkema, S. J.& Hubscher, C. H.. 2016. Training-Induced Functional Gains following SCI. Neural Plasticity،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113144
Modern Language Association (MLA)
Ward, P. Jillian…[et al.]. Training-Induced Functional Gains following SCI. Neural Plasticity No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1113144
American Medical Association (AMA)
Ward, P. Jillian& Herrity, A. N.& Harkema, S. J.& Hubscher, C. H.. Training-Induced Functional Gains following SCI. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113144