Frequency-Dependent Neural Activity in Patients with Unilateral Vascular Pulsatile Tinnitus
Joint Authors
Han, Lv
Zhaohui, Liu
Fei, Yan
Ting, Li
Pengfei, Zhao
Cheng, Dong
Rui, Li
Wang, Guopeng
Zeng, Rong
Zhang, Ling
Wang, Peng
Gong, Shusheng
Wang, Zhenchang
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Previous resting-state functional magnetic resonance imaging (rs-fMRI) studies have shown that neurological changes are important findings in vascular pulsatile tinnitus (PT) patients.
Here, we utilized rs-fMRI to measure the amplitude of low-frequency fluctuations (ALFF) in forty patients with unilateral PT and forty age-, gender-, and education-matched normal control subjects.
Two different frequency bands (slow-4, 0.027–0.073 Hz, and slow-5, 0.010–0.027 Hz, which are more sensitive to subcortical and cortical neurological signal changes, resp.) were analyzed to examine the intrinsic brain activity in detail.
Compared to controls, PT patients had increased ALFF values mainly in the PCu, bilateral IPL (inferior parietal lobule), left IFG (inferior frontal gyrus), and right IFG/anterior insula and decreased ALFF values in the multiple occipital areas including bilateral middle-inferior occipital lobe.
For the differences of the two frequency bands, widespread ALFF differences were observed.
The ALFF abnormalities in aMPFC/ACC, PCu, right IPL, and some regions of occipital and parietal cortices were greater in the slow-5 band compared to the slow-4 band.
Additionally, the THI score of PT patients was positively correlated with changes in slow-5 and slow-4 band in PCu.
Pulsatile tinnitus is a disease affecting the neurological activities of multiple brain regions.
Slow-5 band is more sensitive in detecting the alternations.
Our results also indicated the importance of pathophysiological investigations in patients with pulsatile tinnitus in the future.
American Psychological Association (APA)
Han, Lv& Pengfei, Zhao& Zhaohui, Liu& Wang, Guopeng& Zeng, Rong& Fei, Yan…[et al.]. 2016. Frequency-Dependent Neural Activity in Patients with Unilateral Vascular Pulsatile Tinnitus. Neural Plasticity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113163
Modern Language Association (MLA)
Han, Lv…[et al.]. Frequency-Dependent Neural Activity in Patients with Unilateral Vascular Pulsatile Tinnitus. Neural Plasticity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1113163
American Medical Association (AMA)
Han, Lv& Pengfei, Zhao& Zhaohui, Liu& Wang, Guopeng& Zeng, Rong& Fei, Yan…[et al.]. Frequency-Dependent Neural Activity in Patients with Unilateral Vascular Pulsatile Tinnitus. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113163
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113163