Spindle Activity Orchestrates Plasticity during Development and Sleep
Joint Authors
Lindemann, Christoph
Ahlbeck, Joachim
Bitzenhofer, Sebastian H.
Hanganu-Opatz, Ileana L.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-16
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Spindle oscillations have been described during early brain development and in the adult brain.
Besides similarities in temporal patterns and involved brain areas, neonatal spindle bursts (NSBs) and adult sleep spindles (ASSs) show differences in their occurrence, spatial distribution, and underlying mechanisms.
While NSBs have been proposed to coordinate the refinement of the maturating neuronal network, ASSs are associated with the implementation of acquired information within existing networks.
Along with these functional differences, separate synaptic plasticity mechanisms seem to be recruited.
Here, we review the generation of spindle oscillations in the developing and adult brain and discuss possible implications of their differences for synaptic plasticity.
The first part of the review is dedicated to the generation and function of ASSs with a particular focus on their role in healthy and impaired neuronal networks.
The second part overviews the present knowledge of spindle activity during development and the ability of NSBs to organize immature circuits.
Studies linking abnormal maturation of brain wiring with neurological and neuropsychiatric disorders highlight the importance to better elucidate neonatal plasticity rules in future research.
American Psychological Association (APA)
Lindemann, Christoph& Ahlbeck, Joachim& Bitzenhofer, Sebastian H.& Hanganu-Opatz, Ileana L.. 2016. Spindle Activity Orchestrates Plasticity during Development and Sleep. Neural Plasticity،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113195
Modern Language Association (MLA)
Lindemann, Christoph…[et al.]. Spindle Activity Orchestrates Plasticity during Development and Sleep. Neural Plasticity No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1113195
American Medical Association (AMA)
Lindemann, Christoph& Ahlbeck, Joachim& Bitzenhofer, Sebastian H.& Hanganu-Opatz, Ileana L.. Spindle Activity Orchestrates Plasticity during Development and Sleep. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113195